De Giglio E, Bonifacio MA, Ferreira AM, Cometa S, Ti ZY, Stanzione A, Dalgarno K, Gentile P. Multi-compartment scaffold fabricated via 3D-printing as in vitro co-culture osteogenic model. Scientific Reports. 2018 Oct 11;8(1):15130.
Helling A, Viswanathan P, Cheliotis K, Mobasseri SA, Yang Y, El Haj AJ, Watt FM7. Dynamic culture substrates that mimic the topography of the epidermal-dermal junction. Tissue Engineering Part A. 2018 Oct 3.[Epub ahead of print]
Etxabide A, Ribeiro RDC, Guerrero P, Ferreira AM, Stafford GP, Dalgarno KW, de la Caba K and Gentile P. Lactose-crosslinked fish gelatin-based porous scaffolds embedded with tetrahydrocurcumin for cartilage regeneration. International Journal of Biological Macromolecules. 2018 Oct 1;117, 199-208.
Knight C, James S, Kuntin D, Fox J, Newling K, Hollings S, Pennock R, Genever P. Epidermal growth factor can signal via β-catenin to control proliferation of mesenchymal stem cells independently of canonical Wnt signalling. Cellular Signalling. 2018 Oct 1. pii: S0898-6568(18)30249-3. [Epub ahead of print]
Harrison R, Lugo Leija HA, Strohbuecker S, Crutchley J, Marsh S, Denning C, El Haj A, Sottile V. Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing. Current Stem Cell Research & Therapy. 2018 Sep 26;9(1):248.
Ranmuthu CDS, Ranmuthu CKI, Khan WS. Evaluating the Current Literature on Treatments Containing Adipose-Derived Stem Cells for Osteoarthritis: a Progress Update. Current Rheumatology Reports. 2018 Sep 10;20(11):67 Review
Lolli A, Colella F, De Bari C, van Osch GJ. Targeting anti-chondrogenic factors for the stimulation of chondrogenesis: a new paradigm in cartilage repair. Journal of Orthopaedic Research 2018 Sep 3. [Epub ahead of print] Review.
Whitty C, Wardale J and Henson FMD. The regulation of sclerostin by caphepsin K in periodontal ligament cells. Biochemical and Biophysical Research Communications. 2018 Sep 5;503(2):550-555.
Woods S, Barter MJ, Elliott HR, McGillivray CM, Birch MA, Clark IM, Young DA. miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. Matrix Biology. 2018 Sep 5. [Epub ahead of print]
Salam N, Toumpaniari S, Gentile P, Marina Ferreira A, Dalgarno K, Partridge S. Assessment of Migration of Human MSCs through Fibrin Hydrogels as a Tool for Formulation Optimisation. Materials (Basel). 2018 Sep 19;11(9). pii: E1781.
Dressel R, Greinix HT, Holler E, Dickinson AM. Editorial: Cellular Therapies: Past, Present and Future. Frontiers in Immunology. 2018 Aug 30;9:1966 (eCollection 2018)
Tcacencu I, Rodrigues N, Alharbi N, Benning M, Toumpaniari S, Mancuso E, Marshall M, Bretcanu O, Birch MA, McCaskie AW and Dalgarno KW (2018) Osseointegration of porous apatite-wollastonite and poly (lactic acid) composite structures created using 3D printing techniques. Materials Science and Engineering: C. 2018 Aug;90, 1-7
Duan P, Toumpaniari R, Partridge S, Birch MA, Genever PA, Bull SJ, Dalgarno KW, McCaskie AW and Chen J. How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: An experimental and modelling study. Materials Science and Engineering: C. 2018 Aug.;89, 149-159
Steinberg J, Brooks RA, Southam L, Bhatnagar S, Roumeliotis TI, Hatzikotoulas K, Zengini E, Wilkinson JM, Choudhary JS, McCaskie AW and Zeggini E. Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology (Oxford). 2018 Aug 1;57(8):1481-1489
Norden J, Pearce KF, Irving JAE, Collin MP, Wang XN, Wolff D, Kolb HJ, Socie G, Kuzmina Z, Greinix H, Holler E, Rocha V, Gluckman E, Hromadnikova I, Dickinson AM. The influence of glucocorticoid receptor single nucleotide polymorphisms on outcome after haematopoietic stem cell transplantation. International Journal of Immunogenetics. 2018 Jul 25. [Epub ahead of print]
Atarod S, Norden J, Bibby LA, Janin A, Ratajczak P, Lendrem C, Pearce KF, Wang XN, O’Reilly S, Van Laar JM, Collin M, Dickinson AM, Crossland RE. Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease. Frontiers in Immunology. 2018 Jul 10;9:1485
Turmezei TD, Treece GM, Gee AH, Houlden R, Poole KES. A new quantitative 3D approach to imaging of structural joint disease. Scientific Reports. 2018 Jun 18;8(1):9280
Galarza Torre A, Shaw JE, Wood A, Gilbert HTJ, Dobre O, Genever P, Brennan K, Richardson, S.M. and Swift, J. An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Scientific Reports. 2018 Jun 12;8(1):8981.
Johnson-Lynn SE, McCaskie AW, Coll AP and Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone & Joint Research. 2018 Jun 5;7(5):373-378
Ardakani AHG, Khan WS . The influence of ageing and gender in musculoskeletal stem cell. Current Stem Cell Research & Therapy. 2018 13(6), 432-437
de Bari C and Roelofs AJ. Stem cell-based therapeutic strategies for cartilage defects and osteoarthritis. Current Opinion in Pharmacology. 2018 Jun;40:74-80. Review.
Baird A, Lindsay T, Everett A, Iyemere V, Paterson YZ, McClellan A, Henson FMD and Guest DJ. Osteoblast differentiation of equine induced pluripotent stem cells. Biology Open. 2018 May 10; 7(5)
MacKay JW, Kapoor G, Driban JB, Lo GH, McAlindon TE, Toms AP, McCaskie AW and Gilbert FJ. Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study. European Radiology. 2018 May 2. [Epub ahead of print]
Sykes JG, Kuiper JH, Richardson JB, Roberts S, Wright KT, Kuiper NJ. Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. European Cells & Materials. 2018 May 1;35:255-267.
Khan H, Mafi P, Mafi R, Khan W. The effects of ageing on differentiation and characterisation of human mesenchymal stem cells. Current stem cell research & therapy. 2018 13 (5), 378-383
Hodgson B, Mafi R, Mafi P, Khan WS. The Regulation of Differentiation of Mesenchymal Stem-cells into Skeletal Muscle: A Look at Signalling Molecules Involved in Myogenesis. Current stem cell research & therapy. 2018 13 (5), 384-407
Hulme CH, Wilson EL, Fuller HR, Roberts S, Richardson JB, Gallacher P, Peffers MJ, Shirran SL, Botting CH, Wright KT. Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation. Arthritis Research & Therapy. 2018 May 2018 2;20(1):87.
Newell, K, Chitty, J, Henson FMD. Patient reported outcome following experimental surgery – using telemetry to assess movement in experimental ovine models. Journal of Orthopaedic Research. 2018 May;36(5):1498-1507
Gee AH, Treece GM, Poole KE. How Does the Femoral Cortex Depend on Bone Shape? A Methodology for the Joint Analysis of Surface Texture and Shape. Medical Image Analysis. 2018 Apr 45:55-67
Mcilroy GD, Suchacki K, Roelofs AJ, Yang W, Fu Y, Bai B, Wallace RJ, de Bari C., Cawthorn WP, Han W, Delibegović M. and Rochford JJ. Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease. Molecular Metabolism. 2018 Apr;10:55-65.
Khan S, Mafi P, Mafi R, Khan W. A Systematic Review of Mesenchymal Stem Cells in Spinal Cord Injury, Intervertebral Disc Repair and Spinal Fusion. Current stem cell research & therapy. 2018 13 (4), 316-323
Killington K, Mafi R, Mafi P, Khan WS. A systematic review of clinical studies investigating mesenchymal stem cells for fracture non-union and bone defects. Current stem cell research & therapy. 2018 13 (4), 284-291
Mennan C, Garcia J, McCarthy H, Owen S, Perry J, Wright K, Banerjee R, Richardson JB, Roberts S. Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential. Cartilage. 2018 Apr 1. [Epub ahead of print]
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics. 2018 Apr;50(4):549-558.
Markides H, McLaren JS, Telling ND, Alom N, Al-Mutheffer EA, Oreffo ROC, Zannettino A, Scammell BE, White LJ, El Haj AJ. Translation of remote control regenerative technologies for bone repair. Nature Partner Journals: Regenerative Medicine. 2018 Apr 17;3:9. eCollection 2018.
Kay, A. G., Stone, A., Fox, J. M. & Genever, P. G. CD317 profiling distinguishes bone marrow stromal cell subtypes with distinct functional impact upon T cell proliferation and polarisation. Osteoarthritis and Cartilage 2018 Apr Vol. 26 S296-S297
Mennan C, Roberts S, Garcia JK, Hulme C, Wright K. Assessing the characteristics of human mesenchymal stromal cells derived from bone marrow and umbilical cord following expansion in the quantum® hollow-fibre bioreactor system. Osteoarthritis and Cartilage. 2018 Apr; Vol. 26, S146–S147
Garcia JK, Mennan C, Roberts S, Richardson J, Gallagher P, Wright K. Characterisation of synovial fluid cells of early osteoarthritis patients. Osteoarthritis and Cartilage. 2018 Apr; Vol. 26, S128–S129
Khan WS Outcomes of alveolar soft part sarcoma from a regional tumour unit. Acta Orthopaedica Belgica. 2018 Apr [online]
Sano H, Kondo N, Shimakura T, Fujisawa J, Kijima Y, Kanai T, Poole KES, Yamamoto N, Takahashi HE, Endo N. Evidence for ongoing modeling-based bone formation in human femoral head trabeculae via forming minimodeling structures. A study in patients with fractures and arthritis. Frontiers in Endocrinology. 2018 Mar 19;9:88
MacKay JW, Low SBL, Smith TO, Toms AP, McCaskie AW. and Gilbert FJ. Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. Osteoarthritis and Cartilage. 2018 Mar 14. [Epub ahead of print]
Reis M, McDonald D, Nicholson L, Godthardt K, Knobel S, Dickinson AM, Filby A and Wang X-N. Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry. Scientific Reports. 2018, Mar 2; 8(1), 3907.
Borakati A, Mafi R, Mafi P, Khan WS. A systematic review and meta-analysis of clinical trials of mesenchymal stem cell therapy for cartilage repair. Current stem cell research & therapy. 2018 13 (3), 215-225
Gillies D, Gamal W, Downes A, Reinwald Y, Yang Y, El Haj AJ, Bagnaninchi PO. Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy. Methods. 2018 Mar 1;136:126-133
Gonçalves AI, Rotherham M, Markides H, Rodrigues MT, Reis RL, Gomes ME, El Haj AJ. Triggering the activation of Activin A type II receptor in human adipose stem cells towards tenogenic commitment using mechanomagnetic stimulation. Nanomedicine. 2018 Feb 20;14(4):1149-1159. [Epub ahead of print]
Wilson KM, Jagger AM, Walker M, Seinkmane E, Fox JM, Kröger R, Genever P, Ungar D. Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts. Journal of Cell Science. 2018 Feb 14; 14;131(4)
Lydon H, Brooks R, McCaskie A, Henson F. Peripheral mononuclear blood cell apheresis in a preclinical ovine model. Veterinary Research. 2018 Feb 13;14(1):47.
Wall M, Butler D, El Haj A, Bodle JC, Loboa EG, Banes AJ. Key developments that impacted the field of mechanobiology and mechanotransduction. Journal of Orthopaedic Research. 2018 Feb;36(2):605-619.
Brown SJ, Turner, SA, Balain BS, Davidson NT, Roberts S. Is Osteogenic Differentiation of Human Nucleus Pulposus Cells a Possibility for Biological Spinal Fusion? Cartilage. 2018 Jan 1. [Epub ahead of print]
Briggs W, Guevel B, McCaskie AW and McDonnell SM. Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Annals of the Royal College of Surgeons of England. 2018 Jan;100(1):42-46.
Hopper N, Henson FMD. (2017) Increased sclerostin associated with stress fracture of the third metacarpal bone in the TB racehorse. Bone and Joint Research. 2018 Jan;7(1):94-102.
Books and Chapters
Henson FMD (2018) Equine Neck and Back Pathology 2nd Edition. Wiley, UK.
Williams N, O’Connell PR and McCaskie AW (Editors) (2018) Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McCaskie AW and Bradley A (2018) Tissue Engineering and Regeneration Part 1: Basic Principles, ch.4, pp.33-41. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McDonnell SM and Pandit HG (2018) History taking and clinical examination in musculoskeletal disease. Part 5: Elective Orthopaedics, ch.31 pp.436-462. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Khanduja V and Khan W (2018) Hip and Knee Part 5: Elective Orthopaedics, ch.35 pp.511-523. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Seah MKT, Khan W (2018) Minimally Invasive Surgery of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.5 pp.73-85
Seah MKT, Khan W (2018) Computer-Assisted Navigation of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.6 pp.87-99