2020
Mennan C, Hopkins T, Channon A, Elliott M, Johnstone B, Kadir T, Loughlin J, Peffers M, Pitsillides A, Sofat N, Stewart C, Watt F, Zeggini E, Holt C, Roberts S. The Use of Technology in the Subcategorisation of Osteoarthritis: a Delphi Study Approach. Osteoarthritis and Cartilage Open (In Press)
Garcia J, Hulme C, Mennan C, Roberts S, Bastiaansen-Jenniskens YM, van Osch GJVM, Tins B, Gallacher P, Wright K. The synovial fluid from patients with focal cartilage defects contains mesenchymal stem/stromal cells and macrophages with pro- and anti-inflammatory phenotypes. Osteoarthritis and Cartilage Open (In Press)
Perry J, McCarthy HS, Bou-Gharios G, van ‘t Hof R, Milner PI, Mennan C, Roberts S. Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis. Osteoarthritis and Cartilage Open (In Press)
Zhang H, Whalley RD, Ferreira AM, Dalgarno K. High throughput physiological micro-models for in vitro pre-clinical drug testing: a review of engineering systems approaches. Progress in Biomedical Engineering. 2020 May 22;2(2)
Kaggie JD, Markides H, Graves MJ, MacKay J, Houston G, El Haj A, Gilbert F, Henson FMD. Ultra Short Echo Time MRI of Iron-Labelled Mesenchymal Stem Cells in an Ovine Osteochondral Defect Model. Sci Rep. 2020 May 21;10(1):8451.
Paterson YZ, Cribbs A, Espenel M, Smith EJ, Henson FMD, Guest DJ. Genome-wide transcriptome analysis reveals equine embryonic stem cell-derived tenocytes resemble fetal, not adult tenocytes. Stem Cell Research & Therapy 2020 May 19;11(184)
Samartzis D, Blumenthal S, Fairbank J, Fraser RD, Gunzburg R, Luk KDK, Roberts S, O’Brien JP: 2020 ISSLS Wiltse Lifetime Achievement Award. Spine (Phila Pa 1976). 2020 May 15;45(10):635-640.
Chisari E, Rehak L, Khan WS, Maffulli N. The Role of the Immune System in Tendon Healing: A Systematic Review. Br Med Bull. 2020 May 15;133(1):49-64.
Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS. Evaluating the Effect of Non-cellular Bioactive Glass-Containing Scaffolds on Osteogenesis and Angiogenesis in in vivo Animal Bone Defect Models. Front Bioeng Biotechnol. 2020 May 14;8:430.
Bojanic C, To K, Zhang B, Mak C, Khan WS. Human umbilical cord derived mesenchymal stem cells in peripheral nerve regeneration. World J Stem Cells. 2020 Apr 26;12(4):288-302.
Eisenstein SM, Balain B, Roberts S. Current treatment options for intervertebral disc pathologies. Cartilage 11:143-151. 2020 Apr;11(2):143-151.
Brown SJ, Turner SA, Balain B, Davidson N, Roberts S. (2020) Is osteogenic differentiation of human nucleus pulposus cells a possibility for biological spinal fusion? Cartilage 2020 Apr;11(2):181-191
Hotham WE, Henson FMD. The use of large animals to facilitate the process of MSC going from laboratory to patient-‘bench to bedside’. Cell Biology and Toxicology. 2020 Mar 23 [Epub]
Agarwal N, To K, McDonnell S, Khan W. Clinical and Radiological Outcomes in Robotic-Assisted Total Knee Arthroplasty: A Systematic Review and Meta-Analysis. J Arthroplasty. 2020 Mar 11:S0883-5403(20)30234-5.
Turmezei T, Treece G, Gee A, Sigurdsson S, Jonsson H, Aspelund T, Gudnason V, Poole KES. Quantitative 3D imaging parameters improve prediction of hip osteoarthritis outcome. Scientific Reports 2020 Mar 5;10(1):4127.
Sieberath A, Della Bella E, Ferreira AM, Gentile P, Eglin D, Dalgarno K. A comparison of osteoblast and osteoclast in vitro co-culture models and their translation for preclinical drug testing applications. International Journal of Molecular Sciences. 2020 Feb;21(3):912
Migliorini F, Berton A, Salvatore G, Candela V, Khan W, Longo UG, Denaro V. Autologous Chondrocyte Implantation and Mesenchymal Stem Cells for the Treatments of Chondral Defects Of The Knee- A Systematic Review. Curr Stem Cell Res Ther. 2020 Feb 21.
Roberts S, Kandel R Special Spine Issue Introduction. Cartilage. 2020 Feb 20; 11:141-142
Hernandez PA, Wells J, Usheva E, Nakonezny PA, Barati Z, Gonzalez R, Kassem L, Henson FMD. Early-Onset Osteoarthritis originates at the chondrocyte level in Hip Dysplasia. Sci Rep. 2020 Jan 17;10(1):627.
Kwan H, Chisari E, Khan WS. Cell-Free Scaffolds as a Monotherapy for Focal Chondral Knee Defects. Materials (Basel). 2020 Jan 9;13(2):306.
Chisari E, Yaghmour KM, Peat F, Khan W. Patients Presenting with a Hot, Swollen Joint: A Single-Centre Retrospective Analysis. Curr Rheumatol Rev. 2020;16(1):38-42.
Book Chapters:
De Bari C, Roelofs AJ. Stem and progenitor cells in synovium. Encyclopaedia of Bone Biology (In Press)
Luyten FP, De Bari C, Dell’Accio F. Regenerative Medicine and Tissue Engineering. Kelley’s Textbook of Rheumatology (11th Edition) (In Press)
2019
Assiotis A, To K, Morgan-Jones R, Pengas IP, Khan W. Patellar complications following total knee arthroplasty: a review of the current literature. Eur J Orthop Surg Traumatol. 2019 Dec;29(8):1605-1615.
Pengas I, Nash W, Assiotis A, To K, Khan W, McNicholas M. The effects of knee meniscectomy on the development of osteoarthritis in the patellofemoral joint 40 years following meniscectomy. Eur J Orthop Surg Traumatol. 2019 Dec;29(8):1705-1708.
Dickson BM, Roelofs AJ, Rochford JJ, Wilson HM, De Bari C. The Burden of Metabolic Syndrome on Osteoarthritic Joints. Arthritis Res Ther. 2019 Dec 16; 21 (1): 289.
Chisari E, Rehak L, Khan WS, Maffulli N. Tendon healing in presence of chronic low-level inflammation: a systematic review. Br Med Bull. 2019 Dec 14. pii: ldz035. [Epub ahead of print]
HEALTH Investigators, Bhandari M, Einhorn TA, Guyatt G, Schemitsch EH, Zura RD, Sprague S, Frihagen F, Guerra-Farfán E, Kleinlugtenbelt YV, Poolman RW, Rangan A, Bzovsky S, Heels-Ansdell D, Thabane L, Walter SD, Devereaux PJ. Includes McDonnell SM, Khan WS as collaborators. Total Hip Arthroplasty or Hemiarthroplasty for Hip Fracture. N Engl J Med. 2019 Dec 5;381(23):2199-2208.
To K, Zhang B, Romain K, Mak C, Khan W. Synovium-Derived Mesenchymal Stem Cell Transplantation in Cartilage Regeneration: A PRISMA Review of in vivo Studies. Front Bioeng Biotechnol. 2019 Nov 15;7:314.
Katarivas Levy G, Ong J, Birch M, Justin AW, Markaki A. Albumin-Enriched Fibrin Hydrogel Embedded in Active Ferromagnetic Networks Improves Osteoblast Differentiation and Vascular Self-Organisation. Polymers. 2019;11(11), 1743-1743.
Milne P, Wilhelm-Benartzi C, Grunwald MR, Bigley V, Dillon R, Freeman SD, Gallagher K, Publicover A, Pagan S, Marr H, Jones GL, Dickinson AM, Grech A, Burnett AK, Russell NH, Levis M, Knapper S, Collin M. Blood Adv. 2019 Oct 22;3(20):3052-3061.
Chisari E, Yaghmour KM, Khan WS. The effects of TNF-alpha inhibition on cartilage: a systematic review of preclinical studies. Osteoarthritis Cartilage. 2019 Oct 18. pii: S1063-4584(19)31229-4. [Epub ahead of print] Review.
Scalzone A, Ferreira AM, Tonda-Turo C, Ciardelli G, Dalgarno K, Gentile P. Serum Flt3 ligand is a biomarker of progenitor cell mass and prognosis in acute myeloid leukemia. The interplay between chondrocyte spheroids and mesenchymal stem cells boosts cartilage regeneration within a 3D natural-based hydrogel. Sci Rep. 2019 Oct 10;9(1):14630.
Tanase CE, Qutachi O, White LJ, Shakesheff KM, McCaskie AW, Best SM, Cameron RE. Targeted protein delivery: carbodiimide crosslinking influences protein release from microparticles incorporated within collagen scaffolds. Regen Biomater. 2019 Oct;6(5):279-287.
Souter P, Cunningham JC, Horner A, Genever PG. The variable toxicity of silver ions in cell culture media. Toxicol In Vitro. 2019 Oct;60:154-159.
Devoy B, Yaghmour KM, Chisari E, McDonnell SM, Khan W. Perioperative management of renal transplant patients undergoing total joint arthroplasty. J Perioper Pract. 2019 Sep;29(9):270-275.
Katarivas Levy G, Birch MA, Brooks RA, Neelakantan S, Markaki AE. Stimulation of Human Osteoblast Differentiation in Magneto-Mechanically Actuated Ferromagnetic Fiber Networks. J Clin Med. 2019 Sep 22;8(10). pii: E1522.
To K, Crowley C, Lim SK, Khan WS. Autologous adipose tissue grafting for the management of the painful scar. Cytotherapy. 2019 Nov;21(11):1151-1160. Epub 2019 Sep 17. Review.
Berdichevskia A, Birch MA, Markaki AE. Collagen scaffolds with tailored pore geometry for building three-dimensional vascular networks. Materials Letters. 2019 Aug 1; Vol. 248: 93-96
Mulay A, Truelove A, Prapa M, Casey R, Adler A, Offiah A, Poole KES et al. Identification of novel pathogenic variants and features in patients with pseudohypoparathyroidism and acrodysostosis, subtypes of the newly classified inactivating PTH/PTHrP signalling disorders (iPPSD). American Journal of Medical Genetics: Part A. 2019 Jul;179(7):1330-1337.
Peters DT, Waller H, Birch MA, Lakey JH. Engineered mosaic protein polymers; a simple route to multifunctional biomaterials. J Biol Eng. 2019 Jun 18;13:54. eCollection 2019.
Mushtaq N, To K, Gooding C, Khan W. Radiological Imaging Evaluation of the Failing Total Hip Replacement. Front Surg. 2019 Jun 18;6:35. doi: 10.3389/fsurg.2019.00035.
Wilson A, Webster A, Genever P. Nomenclature and heterogeneity: consequences for the use of mesenchymal stem cells in regenerative medicine. Regen Med. 2019 Jun;14(6):595-611.
Hartley AE, Poole KES et al. Individuals with High Bone Mass have increased progression of radiographic and clinical features of knee Osteoarthritis. Osteoarthritis and Cartilage. 2019 May 14;S1063-4584(20)31021-9.
Johnson-Lynn SE, McCaskie AW, Coll AP, Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone Joint Res. 2018 Jun 5;7(5):373-378. eCollection 2018 May.
Wilson A, Hodgson-Garms M, Frith JE, Genever P. Multiplicity of Mesenchymal Stromal Cells: Finding the Right Route to Therapy. Front Immunol. 2019 May 16;10:1112. eCollection 2019. Review.
Muller S, Nicholson L, Harbi N, Mancuso E, Jones E, Dickinson A, Wang X, Dalgarno K. Osteogenic potential of heterogeneous and CD271-enriched mesenchymal stromal cells cultured on apatite-wollastonite 3D scaffolds. BMC Biomedical Engineering special issue.
Hourston GJ, Barrett MP, Khan WS, Vindlacheruvu M, McDonnell SM. New drug, new problem: do hip fracture patients taking NOACs experience delayed surgery, longer hospital stay, or poorer outcomes? Hip Int. 2019 Apr 25:1120700019841351.[Epub ahead of print]
Ahmed SS, Whritenour J, Ahmed MM, Bibby L, Darby L, Wang XN, Watson J, Dickinson AM. Evaluation of a human in vitro skin test for predicting drug hypersensitivity reactions. Toxicol Appl Pharmacol. 2019 Apr 15;369:39-48
Rose JB, Sidney LE, Patient J, White LJ, Dua HS, El Haj AJ, Hopkinson A, Rose FRAJ. In vitro evaluation of electrospun blends of gelatin and PCL for application as a partial thickness corneal graft. J Biomed Mater Res A. 2019 Apr;107(4):828-838.
Balzano M, De Grandis M, Vu Manh TP, Chasson L, Bardin F, Farina A, Sergé A, Bidaut G, Charbord P, Hérault L, Bailly AL, Cartier-Michaud A, Boned A, Dalod M, Duprez E, Genever P, Coles M, Bajenoff M, Xerri L, Aurrand-Lions M, Schiff C, Mancini SJC. Nidogen-1 Contributes to the Interaction Network Involved in Pro-B Cell Retention in the Peri-sinusoidal Hematopoietic Stem Cell Niche. Cell Reports. 2019 Mar 19;26(12):3257-3271.e8
Devoy B, Yaghmour KM, Chisari E, McDonnell SM, Khan W. Perioperative management of renal transplant patients undergoing total joint arthroplasty. J Perioper Pract. 2019 Mar 19:1750458919835435
Stamatopoulos A, Stamatopoulos T, Gamie Z, Kenanidis E, Ribeiro RDC, Rankin KS, Gerrand C, Dalgarno K, Tsiridis E. Mesenchymal stromal cells for bone sarcoma treatment: Roadmap to clinical practice. J Bone Oncol. 2019 Mar 19;16:100231.
Mennan C, Garcia J, Roberts S, Hulme C, Wright K. A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells. Stem Cell Res Ther. 2019 Mar 18;10(1):99
Palmer AJR, Ayyar Gupta V, Fernquest S, Rombach I, Dutton SJ, Mansour R, Wood S, Khanduja V, Pollard TCB, McCaskie AW, Barker KL, Andrade TJMD, Carr AJ, Beard DJ, Glyn-Jones S; FAIT Study Group. Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre randomised controlled trial. BMJ. 2019 Feb 7;364:l185.
Yaghmour KM, Chisari E, Khan WS. Single-Stage Revision Surgery in Infected Total Knee Arthroplasty: A PRISMA Systematic Review. J Clin Med. 2019 Feb 2;8(2).
Gater R, Ipek T, Sadiq S, Nguyen D, Jones L, El Haj A, Yang Y. Investigation of Conjunctival Fibrosis Response Using a 3D Glaucoma Tenon’s Capsule + Conjunctival Model. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):605-614.
Ranmuthu CDS, Ranmuthu CKI, Russell JC, Singhania D, Khan WS. Are the Biological and Biomechanical Properties of Meniscal Scaffolds Reflected in Clinical Practice? A Systematic Review of the Literature. Int J Mol Sci. 2019 Feb 1;20(3).
Markides H, Newell KJ, Rudorf H, Ferreras LB, Dixon JE, Morris RH, Graves M, Kaggie J, Henson F, El Haj AJ. Ex vivo MRI cell tracking of autologous mesenchymal stromal cells in an ovine osteochondral defect model. Stem Cell Res Ther. 2019 Jan 11;10(1):25.
Tsekes D, Konstantopoulos G, Khan WS, Rossouw D, Elvey M, Singh J. Use of stem cells and growth factors in rotator cuff tendon repair. Eur J Orthop Surg Traumatol. 2019 Jan 9. [Epub ahead of print]
Lolli A, Colella F, De Bari C, van Osch GJVM. Targeting anti-chondrogenic factors for the stimulation of chondrogenesis: A new paradigm in cartilage repair. J Orthop Res. 2019 Jan;37(1):12-22.
Roelofs AJ, De Bari C. Immunostaining of Skeletal Tissues. Methods Mol Biol. 2019;1914:437-450.
Lydon H, Getgood A, and Henson FMD. Healing of Osteochondral defects via endochondral ossification in an ovine model. Cartilage. 2019 10 (1) 94-101.
2018
Lim H, Lim S, Tan C, Thiam C, Goh C, Carbajo D, Chew S, See P, Chakarov S, Wang X, Lim L, Johnson L, Lum J, Fong C, Bongso A, Biswa A, Goh C, Evrard M, Yeo K, Basu R, Wang J, Tan Y, Jain R, Tikoo S, Choong C, Weninge W, Poidinger M, Stanley R, Collin M, Tan N, Ng L, Jackson D, Ginhoux F, Angeli V. Hyaluronan Receptor LYVE-1-Expressing Macrophages Maintain Arterial Tone through Hyaluronan-Mediated Regulation of Smooth Muscle Cell Collagen. Immunity. 2018 Dec;49(2), 326-341.
da Conceicao Ribeiro R, Pal D, Ferreira AM, Gentile P, Benning M, Dalgarno K. Reactive jet impingement bioprinting of high cell density gels for bone microtissue fabrication. Biofabrication. 2018 Dec 27;11(1):015014.
Bhattacharjee A, Kuiper JH, Roberts S, Harrison P, Cassar-Pullicino V, Tins B, Bajada S, Richardson J. Predictors of fracture healing in patients with recalcitrant nonunions treated with autologous culture expanded bone marrow-derived mesenchymal stromal cells. J Orthop Res. 2018 Nov 26.
Markides H, McLaren JS, Telling ND, Alom N, Al-Mutheffer EA, Oreffo ROC, Zannettino A, Scammell BE, White LJ, El Haj AJ. Translation of remote control regenerative technologies for bone repair. Nature Partner Journals: Regen. Med. (vol.1 2016) 2018 Nov 17;3:9. eCollection 2018.
Reis M, Mavin E, Nicholson L, Green K, Dickinson AM, Wang XN. Mesenchymal Stromal Cell-Derived Extracellular Vesicles Attenuate Dendritic Cell Maturation and Function. Front Immunol. 2018 Nov 9;9:2538. eCollection 2018.Moser C, Bardsley K, El Haj AJ, Alini M, Stoddart MJ, Bara JJ. A Perfusion Culture System for Assessing Bone Marrow Stromal Cell Differentiation on PLGA Scaffolds for Bone Repair. Front Bioeng Biotechnol. 2018 Nov 15;6:161.
Marshall J, Barnes AL, Genever PG. Analysis of the intrinsic self-organising properties of mesenchymal stromal cells in three-dimensional co-culture models with endothelial cells. Bioengineering. 2018 Oct 26;5(4). pii: E92.
Ahmed FW, Bakhashab S, Bastaman IT, Crossland RE, Glanville M, Weaver JU. Anti-Angiogenic miR-222, miR-195, and miR-21a Plasma Levels in T1DM Are Improved by Metformin Therapy, Thus Elucidating Its Cardioprotective Effect: The MERIT Study. International Journal of Molecular Sciences. 2018, Oct 19; 19(10), 3242.
De Giglio E, Bonifacio MA, Ferreira AM, Cometa S, Ti ZY, Stanzione A, Dalgarno K, Gentile P. Multi-compartment scaffold fabricated via 3D-printing as in vitro co-culture osteogenic model. Scientific Reports. 2018 Oct 11;8(1):15130.
Helling A, Viswanathan P, Cheliotis K, Mobasseri SA, Yang Y, El Haj AJ, Watt FM7. Dynamic culture substrates that mimic the topography of the epidermal-dermal junction. Tissue Engineering Part A. 2018 Oct 3.[Epub ahead of print]
Etxabide A, Ribeiro RDC, Guerrero P, Ferreira AM, Stafford GP, Dalgarno KW, de la Caba K and Gentile P. Lactose-crosslinked fish gelatin-based porous scaffolds embedded with tetrahydrocurcumin for cartilage regeneration. International Journal of Biological Macromolecules. 2018 Oct 1;117, 199-208.
Knight C, James S, Kuntin D, Fox J, Newling K, Hollings S, Pennock R, Genever P. Epidermal growth factor can signal via β-catenin to control proliferation of mesenchymal stem cells independently of canonical Wnt signalling. Cellular Signalling. 2018 Oct 1. pii: S0898-6568(18)30249-3. [Epub ahead of print]
Gillies D, Gamal W, Downes A, Reinwald Y, Yang Y, El Haj AJ, Bagnaninchi PO. Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy. Methods. 2018 Oct 1;136:126-133
Briggs W, Guevel B, McCaskie AW, McDonnell SM. Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Annals of the Royal College of Surgeons of England. 2018 Oct ;100(1):42-46
Harrison R, Lugo Leija HA, Strohbuecker S, Crutchley J, Marsh S, Denning C, El Haj A, Sottile V. Development and validation of broad-spectrum magnetic particle labelling processes for cell therapy manufacturing. Current Stem Cell Research & Therapy. 2018 Sep 26;9(1):248.
Ranmuthu CDS, Ranmuthu CKI, Khan WS. Evaluating the Current Literature on Treatments Containing Adipose-Derived Stem Cells for Osteoarthritis: a Progress Update. Current Rheumatology Reports. 2018 Sep 10;20(11):67 Review
Whitty C, Wardale J and Henson FMD. The regulation of sclerostin by caphepsin K in periodontal ligament cells. Biochemical and Biophysical Research Communications. 2018 Sep 5;503(2):550-555.
Woods S, Barter MJ, Elliott HR, McGillivray CM, Birch MA, Clark IM, Young DA. miR-324-5p is up regulated in end-stage osteoarthritis and regulates Indian Hedgehog signalling by differing mechanisms in human and mouse. Matrix Biology. 2018 Sep 5. [Epub ahead of print]
Salam N, Toumpaniari S, Gentile P, Marina Ferreira A, Dalgarno K, Partridge S. Assessment of Migration of Human MSCs through Fibrin Hydrogels as a Tool for Formulation Optimisation. Materials (Basel). 2018 Sep 19;11(9). pii: E1781.
Montalbano G, Toumpaniari S, Popov A, Duan P, Chen J, Dalgarno K, Scott WE 3rd, Ferreira AM. Synthesis of bioinspired collagen/alginate/fibrin based hydrogels for soft tissue engineering. Materials (Basel). 2018 Sep 19;11(9). pii: E1781. [2018 report: in press]
Borakati A, Mafi R, Mafi P, Khan WS. A systematic review and meta-analysis of clinical trials of mesenchymal stem cell therapy for cartilage repair. Current Stem Cell Research & Therapy Sep 2018 13(3), 215-225
Dressel R, Greinix HT, Holler E, Dickinson AM. Editorial: Cellular Therapies: Past, Present and Future. Frontiers in Immunology. 2018 Aug 30;9:1966 (eCollection 2018)
Tcacencu I, Rodrigues N, Alharbi N, Benning M, Toumpaniari S, Mancuso E, Marshall M, Bretcanu O, Birch MA, McCaskie AW and Dalgarno KW (2018) Osseointegration of porous apatite-wollastonite and poly (lactic acid) composite structures created using 3D printing techniques. Materials Science and Engineering: C. 2018 Aug;90, 1-7
Duan P, Toumpaniari R, Partridge S, Birch MA, Genever PA, Bull SJ, Dalgarno KW, McCaskie AW and Chen J. How cell culture conditions affect the microstructure and nanomechanical properties of extracellular matrix formed by immortalized human mesenchymal stem cells: An experimental and modelling study. Materials Science and Engineering: C. 2018 Aug.;89, 149-159
Hopper N, Henson FMD. Increased sclerostin associated with stress fracture of the third metacarpal bone in the TB racehorse. Bone & Joint Research 2018 Aug 7(1):94-102
Mccarthy HS, Mccall IW, Williams JM, Mennan C, Dugard MN, Richardson JB, Roberts S. Magnetic Resonance Imaging parameters at 1 year correlate with clinical outcomes up to 17 Years after autologous chondrocyte implantation. Orthopaedic Journal of Sports Medicine 2018 Aug 7; 6(8):2325967118788280.
Steinberg J, Brooks RA, Southam L, Bhatnagar S, Roumeliotis TI, Hatzikotoulas K, Zengini E, Wilkinson JM, Choudhary JS, McCaskie AW and Zeggini E. Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology (Oxford). 2018 Aug 1;57(8):1481-1489
Reis M, McDonald D, Nicholson L, Godthardt K, Knobel S, Dickinson AM, Filby A, Wang XN. Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry. Scientific Reports 2018, 8(1), 3907.
Norden J, Pearce KF, Irving JAE, Collin MP, Wang XN, Wolff D, Kolb HJ, Socie G, Kuzmina Z, Greinix H, Holler E, Rocha V, Gluckman E, Hromadnikova I, Dickinson AM. The influence of glucocorticoid receptor single nucleotide polymorphisms on outcome after haematopoietic stem cell transplantation. International Journal of Immunogenetics. 2018 Jul 25. [Epub ahead of print]Archer DE, Mafi R, Mafi P, Khan W. Preclinical Studies on Biomaterial Scaffold use in Knee Ligament Regeneration: A systematic review. Current Stem Cell Research & Therapy. 2018;13(8):691-701
Atarod S, Norden J, Bibby LA, Janin A, Ratajczak P, Lendrem C, Pearce KF, Wang XN, O’Reilly S, Van Laar JM, Collin M, Dickinson AM, Crossland RE. Differential MicroRNA Expression Levels in Cutaneous Acute Graft-Versus-Host Disease. Frontiers in Immunology. 2018 Jul 10;9:1485
Turmezei TD, Treece GM, Gee AH, Houlden R, Poole KES. A new quantitative 3D approach to imaging of structural joint disease. Scientific Reports. 2018 Jun 18;8(1):9280
Lydon H, Brooks R, McCaskie A, Henson F. Peripheral mononuclear blood cell apheresis in a preclinical ovine model. Veterinary Research 2018 Jun 13;14(1):47 [2018 report: in press]
Johnson-Lynn SE, McCaskie AW, Coll AP and Robinson AHN. Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy. Bone & Joint Research. 2018 Jun 5;7(5):373-378Galarza Torre A, Shaw JE, Wood A, Gilbert HTJ, Dobre O, Genever P, Brennan K, Richardson, S.M. and Swift, J. An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Scientific Reports. 2018 Jun 12;8(1):8981.
Brown SJ, Turner, SA, Balain BS, Davidson NT, Roberts S. Is Osteogenic Differentiation of Human Nucleus Pulposus Cells a Possibility for Biological Spinal Fusion? Cartilage 2018 Jun 1. [Epub ahead of print]
Mennan C, Garcia J, McCarthy H, Owen S, Perry J, Wright K, Banerjee R, Richardson JB, Roberts S. Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential. Cartilage 2018 Jun 1. [Epub ahead of print]
De Bari C and Roelofs AJ. Stem cell-based therapeutic strategies for cartilage defects and osteoarthritis. Current Opinion in Pharmacology. 2018 Jun;40:74-80. Review.Ardakani AHG, Khan WS . The influence of ageing and gender in musculoskeletal stem cell. Current Stem Cell Research & Therapy. 2018 13(6), 432-437
Wall M, Butler D, El Haj A, Bodle JC, Loboa EG, Banes AJ. Key developments that impacted the field of mechanobiology and mechanotransduction. Journal of Orthopaedic Research 2018 May 36(2):605-619
Sano H, Kondo N, Shimakura T, Fujisawa J, Kijima Y, Kanai T, Poole KES, Yamamoto N, Takahashi HE, Endo N. Evidence for ongoing modeling-based bone formation in human femoral head trabeculae via forming minimodeling structures. A study in patients with fractures and arthritis. Frontiers in Endocrinology. 2018 May 19;9:88
Baird A, Lindsay T, Everett A, Iyemere V, Paterson YZ, McClellan A, Henson FMD and Guest DJ. Osteoblast differentiation of equine induced pluripotent stem cells. Biology Open. 2018 May 10; 7(5)
MacKay JW, Kapoor G, Driban JB, Lo GH, McAlindon TE, Toms AP, McCaskie AW and Gilbert FJ. Association of subchondral bone texture on magnetic resonance imaging with radiographic knee osteoarthritis progression: data from the Osteoarthritis Initiative Bone Ancillary Study. European Radiology. 2018 May 2. [Epub ahead of print]
Sykes JG, Kuiper JH, Richardson JB, Roberts S, Wright KT, Kuiper NJ. Impact of human platelet lysate on the expansion and chondrogenic capacity of cultured human chondrocytes for cartilage cell therapy. European Cells & Materials. 2018 May 1;35:255-267.
Khan H, Mafi P, Mafi R, Khan W. The effects of ageing on differentiation and characterisation of human mesenchymal stem cells. Current stem cell research & therapy. 2018 13 (5), 378-383
Hodgson B, Mafi R, Mafi P, Khan WS. The Regulation of Differentiation of Mesenchymal Stem-cells into Skeletal Muscle: A Look at Signalling Molecules Involved in Myogenesis. Current stem cell research & therapy. 2018 13 (5), 384-407
Hulme CH, Wilson EL, Fuller HR, Roberts S, Richardson JB, Gallacher P, Peffers MJ, Shirran SL, Botting CH, Wright KT. Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation. Arthritis Research & Therapy. 2018 May 2018 2;20(1):87.
Newell, K, Chitty, J, Henson FMD. Patient reported outcome following experimental surgery – using telemetry to assess movement in experimental ovine models. Journal of Orthopaedic Research. 2018 May;36(5):1498-1507
Gill EL, Li X, Birch MA, Huang YYS. Multi-length scale bioprinting towards simulating microenvironmental cues. Biodes Manuf. 2018;1(2):77-88.
Gee AH, Treece GM, Poole KE. How Does the Femoral Cortex Depend on Bone Shape? A Methodology for the Joint Analysis of Surface Texture and Shape. Medical Image Analysis. 2018 Apr 45:55-67
Gonçalves AI, Rotherham M, Markides H, Rodrigues MT, Reis RL, Gomes ME, El Haj AJ. Triggering the activation of Activin A type II receptor in human adipose stem cells towards tenogenic commitment using mechanomagnetic stimulation. Nanomedicine. 2018 Apr 20;14(4):1149-1159. [Epub ahead of print]
Wilson KM, Jagger AM, Walker M, Seinkmane E, Fox JM, Kröger R, Genever P, Ungar, D. Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts. Journal of Cell Science. 2018 Apr 14;131(4)
Galarza Torre A, Shaw JE, Wood A, Gilbert HTJ, Dobre O, Genever P, Brennan K, Richardson SM, Swift, J. An immortalised mesenchymal stem cell line maintains mechano-responsive behaviour and can be used as a reporter of substrate stiffness. Scientific Reports 2018 Apr 12;8(1):8981
Mcilroy GD, Suchacki K, Roelofs AJ, Yang W, Fu Y, Bai B, Wallace RJ, de Bari C., Cawthorn WP, Han W, Delibegović M. and Rochford JJ. Adipose specific disruption of seipin causes early-onset generalised lipodystrophy and altered fuel utilisation without severe metabolic disease. Molecular Metabolism. 2018 Apr;10:55-65.
Khan S, Mafi P, Mafi R, Khan W. A Systematic Review of Mesenchymal Stem Cells in Spinal Cord Injury, Intervertebral Disc Repair and Spinal Fusion. Current stem cell research & therapy. 2018 13 (4), 316-323
Killington K, Mafi R, Mafi P, Khan WS. A systematic review of clinical studies investigating mesenchymal stem cells for fracture non-union and bone defects. Current stem cell research & therapy. 2018 13 (4), 284-291
Mennan C, Garcia J, McCarthy H, Owen S, Perry J, Wright K, Banerjee R, Richardson JB, Roberts S. Human Articular Chondrocytes Retain Their Phenotype in Sustained Hypoxia While Normoxia Promotes Their Immunomodulatory Potential. Cartilage. 2018 Apr 1. [Epub ahead of print]
Zengini E, Hatzikotoulas K, Tachmazidou I, Steinberg J, Hartwig FP, Southam L, Hackinger S, Boer CG, Styrkarsdottir U, Gilly A, Suveges D, Killian B, Ingvarsson T, Jonsson H, Babis GC, McCaskie A, Uitterlinden AG, van Meurs JBJ, Thorsteinsdottir U, Stefansson K, Davey Smith G, Wilkinson JM, Zeggini E. Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics. 2018 Apr;50(4):549-558.
Markides H, McLaren JS, Telling ND, Alom N, Al-Mutheffer EA, Oreffo ROC, Zannettino A, Scammell BE, White LJ, El Haj AJ. Translation of remote control regenerative technologies for bone repair. Nature Partner Journals: Regenerative Medicine. 2018 Apr 17;3:9. eCollection 2018.
Kay AG, Stone A, Fox JM, Genever PG. CD317 profiling distinguishes bone marrow stromal cell subtypes with distinct functional impact upon T cell proliferation and polarisation. Osteoarthritis and Cartilage 2018 Apr Vol. 26 S296-S297
Mennan C, Roberts S, Garcia JK, Hulme C, Wright K. Assessing the characteristics of human mesenchymal stromal cells derived from bone marrow and umbilical cord following expansion in the quantum® hollow-fibre bioreactor system. Osteoarthritis and Cartilage. 2018 Apr; Vol. 26, S146–S147
Garcia JK, Mennan C, Roberts S, Richardson J, Gallagher P, Wright K. Characterisation of synovial fluid cells of early osteoarthritis patients. Osteoarthritis and Cartilage. 2018 Apr; Vol. 26, S128–S129
Khan WS Outcomes of alveolar soft part sarcoma from a regional tumour unit. Acta Orthopaedica Belgica. 2018 Apr [online]
Sano H, Kondo N, Shimakura T, Fujisawa J, Kijima Y, Kanai T, Poole KES, Yamamoto N, Takahashi HE, Endo N. Evidence for ongoing modeling-based bone formation in human femoral head trabeculae via forming minimodeling structures. A study in patients with fractures and arthritis. Frontiers in Endocrinology. 2018 Mar 19;9:88
Mennan C, Garcia J, Roberts S, Hulme C, Wright K. A comprehensive characterisation of large-scale expanded human bone marrow and umbilical cord mesenchymal stem cells. Stem Cell Res Ther. 2019 Mar 18;10(1):99
Reis M, McDonald D, Nicholson L, Godthardt K, Knobel S, Dickinson AM, Filby A and Wang X-N. Global phenotypic characterisation of human platelet lysate expanded MSCs by high-throughput flow cytometry. Scientific Reports. 2018, Mar 2; 8(1), 3907.MacKay JW, Low SBL, Smith TO, Toms AP, McCaskie AW. and Gilbert FJ. Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis. Osteoarthritis and Cartilage. 2018 Mar 14. [Epub ahead of print]
Borakati A, Mafi R, Mafi P, Khan WS. A systematic review and meta-analysis of clinical trials of mesenchymal stem cell therapy for cartilage repair. Current stem cell research & therapy. 2018 13 (3), 215-225
Gillies D, Gamal W, Downes A, Reinwald Y, Yang Y, El Haj AJ, Bagnaninchi PO. Real-time and non-invasive measurements of cell mechanical behaviour with optical coherence phase microscopy. Methods. 2018 Mar 1;136:126-133
Gonçalves AI, Rotherham M, Markides H, Rodrigues MT, Reis RL, Gomes ME, El Haj AJ. Triggering the activation of Activin A type II receptor in human adipose stem cells towards tenogenic commitment using mechanomagnetic stimulation. Nanomedicine. 2018 Feb 20;14(4):1149-1159. [Epub ahead of print]
Wilson KM, Jagger AM, Walker M, Seinkmane E, Fox JM, Kröger R, Genever P, Ungar D. Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts. Journal of Cell Science. 2018 Feb 14; 14;131(4)
Lydon H, Brooks R, McCaskie A, Henson F. Peripheral mononuclear blood cell apheresis in a preclinical ovine model. Veterinary Research. 2018 Feb 13;14(1):47.
Wall M, Butler D, El Haj A, Bodle JC, Loboa EG, Banes AJ. Key developments that impacted the field of mechanobiology and mechanotransduction. Journal of Orthopaedic Research. 2018 Feb;36(2):605-619.
Brown SJ, Turner, SA, Balain BS, Davidson NT, Roberts S. Is Osteogenic Differentiation of Human Nucleus Pulposus Cells a Possibility for Biological Spinal Fusion? Cartilage. 2018 Jan 1. [Epub ahead of print]
Briggs W, Guevel B, McCaskie AW and McDonnell SM. Multi- and univariate analyses of the weekend effect for elective lower-limb joint replacements. Annals of the Royal College of Surgeons of England. 2018 Jan;100(1):42-46.
Hopper N, Henson FMD. (2017) Increased sclerostin associated with stress fracture of the third metacarpal bone in the TB racehorse. Bone and Joint Research. 2018 Jan;7(1):94-102.
Books and Chapters
Henson FMD (2018) Equine Neck and Back Pathology 2nd Edition. Wiley, UK.
Williams N, O’Connell PR and McCaskie AW (Editors) (2018) Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McCaskie AW and Bradley A (2018) Tissue Engineering and Regeneration Part 1: Basic Principles, ch.4, pp.33-41. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
McDonnell SM and Pandit HG (2018) History taking and clinical examination in musculoskeletal disease. Part 5: Elective Orthopaedics, ch.31 pp.436-462. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Khanduja V and Khan W (2018) Hip and Knee Part 5: Elective Orthopaedics, ch.35 pp.511-523. In Bailey and Love: Short Practice of Surgery, 27th Edition. CRC Press
Seah MKT, Khan W (2018) Minimally Invasive Surgery of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.5 pp.73-85
Seah MKT, Khan W (2018) Computer-Assisted Navigation of the Hip Joint. In Iyer, K. (Ed.) (2018) Hip Joint in Adults. New York: Pan Stanford. ch.6 pp.87-99
