2017
Newell, K, Chitty, J, Henson FMD. (2017) Patient reported outcome following experimental surgery – using telemetry to assess movement in experimental ovine models. Journal of Orthopaedic Research, In Press.
Hopper N. and Henson FMD. (2017) Increased sclerostin associated with stress fracture of the third metacarpal bone in the TB racehorse.Bone and Joint Research (Bone and Joint Research, In Press).
Lydon H, Getgood A, and Henson FMD. (2017) Healing of Osteochondral defects via endochondral ossification in an ovine model. Cartilage doi: 10.1177/1947603517713818.
Luyten FP, De Bari C, Dell’Accio F. Regenerative Medicine and Tissue Engineering. Book Chapter, Kelley’s Textbook of Rheumatology (10th Edition – in press).
Etheridge L, Mason R, Saleh F, Genever P (2017) Cell-Cell Signalling Pathways that Regulate MSC Differentiation. The Biology and Therapeutic Applications of Mesenchymal Cells. Wiley. ISBN: 978-1-118-90751-1 .2017.
Ribeiro R, Pal D, Jamieson D, Rankin K, Benning M, Dalgarno K, and Ferreira A (2017) Temporary Single Cell Coating for Bioprocessing via a Cationic Polymer. ACS Applied Materials & Interfaces. 9 (15), 12967–12974.doi: 10.1021/acsami.6b16434
Baba Ismail YM, Wimpenny I, Bretcanu O, Dalgarno K, El Haj AJ. (2017) Development of multi-substituted hydroxyapatite nanopowders as biomedical materials for bone tissue engineering applications. Journal of Biomedical Materials Research Part A. doi: 10.1002/jbm.a.36038.
Roelofs AJ, Zupan J, Riemen AHK, Kania K, Ansboro S, White N, Clark SM, De Bari C (2017) Joint morphogenetic cells in the adult mammalian synovium. Nature Communications (in press)
2016
Wright KT, Kuiper JH, Richardson JB, Gallacher P, Roberts S. (2016) The absence of detectable ADAMTS-4 (aggrecanase-1) activity in synovial fluid is a predictive indicator of autologous chondrocyte implantation success. Am J Sports Med (In Press).
Roberts S, Colombier P, Sowman A, Mennan C, Rölfing JHD, Guicheux J, Edwards JR (2016) Ageing in the musculoskeletal system; Cellular function and dysfunction throughout life. Acta Orthop. 87:sup363, 15-25, DOI: 10.1080/17453674.2016.1244750.
Garcia J, Mennan C, Mcarthy HS, Roberts S, Richardson JB, Wright KT (2016) Chondrogenic Potency Analyses of Donor-Matched Chondrocytes and Mesenchymal Stem Cells Derived from Bone Marrow, Infrapatellar Fat Pad, and Subcutaneous Fat. Stem Cells International, Article ID 6969726; doi:10.1155/2016/6969726.
Sharma A, Roberts S, Kuiper NJ (2016) A case study: Glycosaminoglycan profiles of autologous chondrocyte implantation (ACI) tissue improve as the tissue matures. The Knee. 24 (1):149–157.
Mennan C, Brown S, McCarthy H, Mavrogonatou E, Kletsas D, Garcia J, Balain B, Richardson J, Roberts S (2016) Mesenchymal stromal cells derived from whole human umbilical cord exhibit similar properties to those obtained from Wharton’s jelly and bone marrow. FEBS Open Bio 6:1054–1066. doi:10.1002/2211-5463.12104.
Foldager C, Bendtsen M, Berg LC, Brinchmann J, Brittberg M, Bunger C, Canseco J, Chen L, Christensen B, Colombier P, Deleuran BW, Edwards J, Elmengaard B, Farr J, Gatenholm B, GomollL A, Hui J, Jakobson R, Jørgnesen NL, Kassem M, Koch T, Kold S, Krogsgaard M, Lauridsen H, Le D, Le Visage C, Lind M, Nygaard JV, Olesen M, Pedersen M, RathckeM, Richardson J, Roberts S, Duedal Rölfing JH, Sakai D, Toh WS, Urban J, Spector M (2016) Position Paper: Aarhus Regenerative Orthopaedics Symposium (AROS): Regeneration in the Ageing Population. Acta Orthopaedica. 87(2):1-5.
Dugard N, Kuiper J-H, Parker J, Roberts S, Robinson E, Harrison P, Richardson JB (2016) Development of a tool to predict outcome of Autologous Chondrocyte Implantation. CARTILAGE 8(2) (doi: 10.1177/1947603516650002).
Toh WS, Brittberg M, Farr J, Foldager CB, Gomoll AH, Hui JHP, Richardson JB, Roberts S, Spector M (2016) Cellular senescence in aging and osteoarthritis: Implications for cartilage repair. Acta Orthopaedica (2016) 87: DOI:10.1080/17453674.2016.1235087.
Garcia J, Wright K, Roberts S, Kuiper JH, Mangham C, Richardson J, Mennan C. (2016) Characterisation of synovial fluid and infrapatellar fat pad derived mesenchymal stromal cells: The influence of tissue source and inflammatory stimulus. Scientific Reports 13(6):24295.
Turner SA, Wright KT, Jones PN, Balain B, Roberts S (2016) Temporal analyses of the response of intervertebral disc cells and mesenchymal stem cells to nutrient deprivation 2016; Stem Cells International, Volume 2016, Article ID 5415901, 13 pages.
Bhattacharjee A, McCarthy H, Tins B, Roberts S, KuiperJH , Harrison PE, Richardson JB (2016) Autologous bone plug supplemented with Autologous Chondrocyte Implantation in osteochondral defect of the knee. American Journal of Sports Medicine. May;44(5):1249-59.
McCarthy H, Richardson JB, Parker J, Roberts S (2016) Evaluating joint morbidity after chondral harvest for Autologous Chondrocyte Implantation (ACI): a study of ACI treated ankles and hips with a knee chondral harvest. Cartilage. 7:7-15.
Saleh F, Carstairs A, Etheridge SL, Genever P (2016) Real-Time Analysis of Endogenous Wnt Signalling in 3D Mesenchymal Stromal Cells. Stem Cells Int. 2016:7132529. doi: 10.1155/2016/7132529.
Wilson KM, Thomas-Oates JE, Genever PG, Ungar D (2016) Glycan Profiling Shows Unvaried N-Glycomes in MSC Clones with Distinct Differentiation Potentials. Front Cell Dev Biol. May 31;4:52. doi: 10.3389/fcell.2016.00052.
Barnes AL, Genever PG, Rimmer S, Coles MC (2016) Collagen-Poly(N-isopropylacrylamide) Hydrogels with Tunable Properties. Biomacromolecules. 2016 Mar 14;17(3):723-34. doi: 10.1021/acs.biomac.5b01251.
Howard, D, Tanase, E, Wardale, J, and Henson, F. (2016). A novel biphasic scaffold supports meniscal tissue repair in ex vivo and in vivo models. Musculoskeletal Regeneration, 2 (e1411)https://doi.org/10.14800/mr.1411
Sergijenko A, Roelofs AJ, Riemen AH, De Bari C (2016) Bone marrow contribution to synovial hyperplasia following joint surface injury.Arthritis Res Ther. 18:166-176.
Ferreira AM, Gentile P, Toumpaniari S, Ciardelli G, Birch MA (2016) Impact of collagen/heparin multi-layers for regulating bone cellular functions.ACS Appl. Mater. Interfaces. 8(44):29923-29932.
Bendsten DM, Bunger C, Colombier P, Le Visage C, Roberts S, Sakai D, Urban JPG (2016) Biological challenges for regeneration of the degenerated disc using cellular therapies. Acta Orthopaedica. 87 (eSuppl 363): 39–46 39
2015
Karystinou A, Roelofs AJ, Neve A, Cantatore FP, Wackerhage H, De Bari C (2015) Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells. Arthritis Res Ther. 17:147.
Redelinghuys P, Whitehead L, Augello A, Drummond RA, Levesque J-M, Vautier S, Reid DM, Kerscher B, Taylor JA, Nigrovic PA, Wright J, Murray GI, Willment JA, Hocking LJ, Fernandes MJG, De Bari C, Mcinnes IB, Brown GD (2015) MICL controls inflammation in rheumatoid arthritis. Ann Rheum Dis. 2015 Aug 14; doi.10.1136/annrheumdis-2014-206644
Sun S, Błażewska KM, Kadina AP, Kashemirov BA, Duan X, Triffitt JT, Dunford JE, Russell RGG, Ebetino FH, Roelofs AJ, Coxon FP, Lundy MW, McKenna CE (2015) Fluorescent Bisphosphonate and Carboxyphosphonate Probes: A Versatile Imaging Toolkit for Applications in Bone Biology and Biomedicine. Bioconjug Chem. Dec 8.27 (2), 329–340
Haddad FS and McCaskie AW (2015) From needle to knife Bone Jt J. Jan;97-B(1):1–2.
Johnson-Lynn SE, Roy S, McCaskie AW, Birch MA (2015) Electrochemical Modification of Titanium Alloy Influences Osteoblast Morphology and Activity of Cadherin-11 and Rho-Family GTPases J. Biomater. Tissue Eng. 5:857-863.
Roberts S, Evans H, Wright K, van Niekerk L, Caterson B., Richardson JB, Kumar KHS, and Kuiper JH (2015) ADAMTS-4 activity in synovial fluid as a biomarker of inflammation and effusion. Osteoarthr. Cartil. OARS Osteoarthr. Res. Soc. 23: 1622–1626. doi:10.1016/j.joca.2015.05.006 .
Walter MNM, Khan NS, Major T, Fuller HR, Kuiper JH, Wright KT, Johnson WE (2015) Human mesenchymal stem cells stimulate EaHy926 endothelial cell migration: combined proteomic and in vitro analysis of the influence of donor-donor variability. J Stem Cells Regen Med. 11, 18–24 eCollection 2015.
Bara JJ, Turner S, Roberts S, Griffiths G, Benson R, Trivedi JM, Wright KT (2015) High content and high throughput screening to assess the angiogenic and neurogenic actions of mesenchymal stem cells in vitro. Experimental Cell. Apr 10;333(1):93-104. doi: 10.1016/j.yexcr.2014.12.019.
Ryd L, Brittberg M, Eriksson K, Jurvelin J, Lindahl A, Marlovits S, Möller P, Richardson J, Steinwachs M, Zenobi-Wong M (2015) Pre-osteoarthritis: Definition and diagnosis of an elusive clinical entity. Cartilage. Jul;6(3):156-65. doi: 10.1177/1947603515586048.
Kohli N, Wright K, Jeys L, Snow M, Johnson W (2015) An in vitro comparison of the incorporation, growth and chondrogenic potential of human bone marrow versus adipose tissue mesenchymal stem cells in clinically relevant cell scaffolds used for cartilage repair. Cartilage. Oct;6(4):252-63.
Cuthbert RJ, Giannoudis PV, Wang XN, Nicholson L, Pawson D, Lubeenko A, Tan HB, Dickinson AM, McGonagle D, Jone E (2015) Examining the feasibility of clinical grade CD271 enrichment of MSCs for bone regeneration. PLoS ONE 10, e0117855. doi:10.1371/journal.pone.0117855.
Pennock R, Bray E, Pryor P, James S, McKeegan P, Sturmey R, Genever P (2015) Human cell dedifferentiation in mesenchymal condensates through controlled autophagy. Sci Rep. 2015 Aug 20; 5:13113. doi: 10.1038/srep13113.
Lee JA, Knight CA, Kun X, Yang XB, Wood DJ, Dalgarno KW, Genever PG (2015) In vivo biocompatibility of custom-fabricated apatite-wollastonite-mesenchymal stromal cell constructs. J Biomed Mater Res A. Oct;103(10):3188-200. doi: 10.1002/jbm.a.35448.
James S, Fox J, Afsari F, Lee J, Clough S, Knight C, Ashmore J, Ashton P, Preham O, Hoogduijn M, De Almeida R, Ponzoni R , Hancock Y, Coles M, Genever P (2015) Multiparameter analysis of human bone marrow stromal cells identifies distinct immunomodulatory and differentiation-competent subtypes. Stem Cell Reports. Jun 9;4(6):1004-15. doi: 10.1016/j.stemcr.2015.05.005.
Ji B, Genever PG, Fagan MJ (2015) A virtual approach to evaluate therapies for management of multiple myeloma induced bone disease. Int J Numer Method Biomed Eng. Mar;32(3)
Pennock R, Bray E, Pryor P, James S, McKeegan P, Sturmey R, Genever P (2015) Human cell dedifferentiation in mesenchymal condensates through controlled autophagy. Scientific Report. Aug 20;5:13113. doi: 10.1038/srep13113.
Eseonu O, De Bari C (2015) Homing of mesenchymal stem cells: Mechanistic or stochastic? Implications for targeted delivery in arthritis Rheumatology (Oxford) Feb: 54(2):210-8.
De Bari C (2015) Are mesenchymal stem cells in rheumatoid arthritis the good or bad guys? Arthritis Research and Therapy. 17-113.
2014
Cherry, H.M., Roelofs, A.J., Kurth, T.B., De Bari, C (2014) In vivo phenotypic characterisation of nucleoside label-retaining cells in mouse periosteum Eur Cell Mater.27:185-195.
Tremblay AM, Missiaglia E, Galli GG, Hettmer S, Carrara M, Urcia R, Judson RN, Thway K, Nadal G, Selfe JL, Murray G, Calogero RA, De Bari C, Zammit PS, Delorenzi M, Wagers AJ, Shipley J, Wackerhage H, Camargo FD (2014) The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation. Cancer Cell. 26 (2): 273-287.
Sherwood J, Bertrand J, Nalesso G, Poulet B, Pitsillides A, Brandolini L, Karystinou A, De Bari C, Luyten FP, Pitzalis C, Pap T, Dell’Accio F (2014) A homeostatic function of CXCR2 signalling in articular cartilage. Ann. Rheum. Dis. 74, 2207–2215. doi:10.1136/annrheumdis-2014-205546.
Pavlova AV, Meakin JR, Cooper K, Barr RJ, Aspden RM (2014)The lumbar spine has an intrinsic shape specific to each individual that remains a characteristic throughout flexion and extension. Eur Spine J. Apr;23 Suppl 1:S26-32.
Burgin LV, Edelsten L, Aspden RM (2014) The mechanical and material properties of elderly human articular cartilage subject to impact and slow loading Med Eng Phys. 2014 Feb;36(2):226-32.
Merle C, Waldstein W, Gregory JS, Goodyear SR, Aspden RM, Aldinger PR, Murray DW, Gill HS (2014) How many different types of femora are there in primary hip osteoarthritis? An active shape modeling study. J Orthop Res. Mar;32(3):413-22.
Bara JJ , Mccarthy HE, Humphrey E, Johnson WEB, Roberts S (2014) Bone marrow-derived mesenchymal stem cells become anti-angiogenic when chondrogenically and osteogenically differentiated: Implications for bone and cartilage tissue engineering Tissue Engineering, Part A 20:147-59 PMID: 23895198
Leighton R, Akermark C, Therrien R, Richardson JB, Andersson M, Todman MG, Arden NK (2014) NASHA hyaluronic acid vs. methylprednisolone for knee osteoarthritis: a prospective, multi-centre, randomized, non-inferiority trial. Osteoarthritis and Cartilage. Jan;22(1):17-25.
Müller S, Nicholson, de Havilland JR, Dickinson AM, Wang XN (2014) Population kinetics of mesenchymal stem cells in the development of bio-artificial bone scaffolds. Cytotherapy. Vol 16 page 73.
Carstairs A, Genever P (2014) Stem cell treatment for musculoskeletal disease. Curr Opin Pharmacol. Jun;16:1-6. doi: 10.1016/j.coph.2014.01.005
Roberts S, Mccaskie A, Bhattacharjee A, Richardson JB (2014) Cartilage Repair in the Hip. A.A. SHETTY et al (Eds) 2014 Surgical Techniques in Cartilage Repair Surgery, (Springer-Verlag GmbH): Ch23 pp259-266.
Carstairs A, Genever P (2014) Stem cell treatment for musculoskeletal disease. Curr Opin Pharmacol. Feb 18;16C:1-6. doi: 10.1016/j.coph. 2014.01.005.
Fox J, Genever P (2014) Use of adult stem cells for orthopedic regenerative medicine applications. Cell & Tissue Transplantation & Therapy 6 19-25. doi: 10.4137/CTTT.S12277.
